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Diphtheria, Tetanus, Pertussis, Hepatitis B, Polio, and Haemophilus influenzae type b (DTaP-HB-IPV-Hib) vaccine

Date last reviewed: 
Tuesday, May 28, 2024

Available in 简体中文 (Simplified Chinese), 繁體中文 (Traditional Chinese), یسراف (Farsi), 한국어 (Korean), ਪੰਜਾਬੀ (Punjabi), and other languages.

Recommended for babies at 2,4, and 6 months as the best way to protect against diphtheria, tetanus, pertussis, hepatitis B, polio, Haemophilus influenzae type b.

Diseases it protects against

The DTaP-HB-IPV-Hib vaccine protects your child against 6 diseases with 1 vaccine. It protects your child against:
  • Diphtheria
  • Tetanus
  • Pertussis (whooping cough)
  • Hepatitis B
  • Polio
  • Haemophilus influenzae type b
These diseases can cause serious illness, hospitalization, and even death. Learn more about these diseases.

Did you know?

Combination vaccines reduce the number of shots your child needs while protecting against the same number of diseases. These vaccines are as safe and work as well as the vaccines given separately. 

Who should get the vaccine

Age Schedule
Infants & young children
  • 1 dose at 2, 4, and 6 months of age.
For best protection, your child needs to receive all vaccines at the right time.

Did you know?

Vaccines start at a young age because babies are at highest risk of serious complications from many of the diseases vaccines prevent. It’s also best to vaccinate before your child is potentially exposed to dangerous diseases.

How well it works

When a child gets all the recommended doses, the protection is:
  • Almost 100% for diphtheria, tetanus and polio. 
  • Around 85% for pertussis.
  • At least 95% for hepatitis B.
  • Over 95% for Hib.
Your child will need booster shots to maintain their protection against some of these diseases. 
When your child gets immunized, you help protect others as well. People who are immunized are much less likely to catch a preventable disease and spread it to others.

Did you know?

Parents play an important role in supporting their children during immunizations. Check out some tips you can use to help make the immunization experience more positive for you and your child.


Vaccines are very safe. Getting the vaccine is much safer than getting one of the diseases.
Vaccine safety is a top priority in Canada. Every vaccine must be shown to be safe and effective before it is approved for use in Canada. After approval, the safety of vaccines is continuously monitored. Learn more about vaccine safety.

Side effects

Many people have no side effects from vaccines. For those that do, they are usually mild and go away on their own within a few days. Serious side effects are very rare.
Common reactions to the DTaP-HB-IPV-Hib vaccine may include:
  • Soreness, redness and swelling where the vaccine was given. 
  • Some children may have a fever or experience crankiness, drowsiness, loss of appetite, vomiting and diarrhea. 
It is important to stay at the clinic for 15 minutes after your vaccine. Some people may have a rare but serious allergic reaction called anaphylaxis. If anaphylaxis happens, you will get medicine to treat the symptoms.
Let your immunization provider/clinic or health care provider know if you or your child have any serious or unexpected side effects after immunization.

How to manage side effects

For information on how to manage side effects, view the immunization aftercare sheets below.

Who should not get the vaccine

Speak to your health care provider if you or your child:
  • Has had a life-threatening reaction to a previous dose of tetanus, diphtheria, pertussis, hepatitis B, polio or Haemophilus influenzae type b vaccine, or any part of the vaccine, including neomycin and polymyxin B.
  • Developed Guillain-Barré Syndrome (GBS) within 8 weeks of getting a tetanus vaccine, without another cause being identified, as you should not get a tetanus-containing vaccine. GBS is a rare condition that can result in weakness and paralysis of the body's muscles. It most commonly occurs after infections, but in rare cases can also occur after some vaccines.
There is no need to delay getting immunized because of a cold or other mild illness. However, if you have concerns, speak to your health care provider.

Disease quick facts


What is tetanus?

Tetanus is a disease caused by a bacteria that is usually found in dirt and soil. The bacteria make a toxin, or poison, that causes severe muscle spasms. Tetanus can be very dangerous. Tetanus is also called "lockjaw" because muscle spasms in your jaw make it hard to open your mouth.

How does tetanus spread?

Tetanus is caused by bacteria usually found in dirt and soil. The bacteria enter the skin through a cut or scrape and produce a poison that causes the painful tightening of the muscles all over the body. 
Unlike most vaccine-preventable diseases, tetanus does not spread from person to person. Any person not immunized against tetanus is at risk. Immunization is the only way to protect against tetanus.

What are the symptoms and risks?

Tetanus symptoms appear slowly and get worse over time. The time it takes for symptoms to appear after a cut or injury ranges from days to months. In most cases, symptoms of tetanus appear within 14 days.
Tetanus symptoms often begin with a headache and trouble opening your mouth (lockjaw). You also may have trouble swallowing and/or a stiff neck, back, or shoulders.
As the toxin spreads, it can be deadly. It can cause problems with your blood pressure and heart rate. It can cause severe and painful muscle spasms in your neck, arms, legs, and belly.
There is no cure for tetanus. Up to 1 in 5 people who get tetanus may die.

What is diphtheria?

Diphtheria is a very serious infection that can affect your nose and throat or skin. It can also spread through the body and damage the heart and central nervous system. 
Diphtheria is now very rare in Canada because of immunization. 

How does it spread?

The bacteria are spread through the air by people sneezing or coughing or by direct skin-to-skin contact with someone who has diphtheria.

What are the symptoms and risks?

Diphtheria in your nose and throat can cause problems breathing. Symptoms may include:
  • A moderate to severe sore throat
  • Swollen and sore lymph nodes in the neck
  • Swelling of the neck
  • Heart and nervous system complications
Diphtheria in your skin can cause lesions (damaged skin tissue or sores).
Diphtheria can cause severe breathing problems, heart failure and paralysis. One of every 10 people who get diphtheria will die from it.

What is pertussis?

Pertussis (also called whooping cough) is a serious infection of the airways caused by pertussis bacteria. People of any age can get pertussis. Infants and young children who have not been immunized get sicker than older children and adults. If an immunized person gets pertussis, they usually have much milder illness. 

How does it spread?

Pertussis spreads easily when an infected person coughs, sneezes or has close contact with others. Sharing food, drinks or cigarettes, or kissing someone who has the pertussis bacteria can also put you at risk. Pertussis can be spread to others during the early stages of the infection when symptoms are not severe and if left untreated, it can spread up to 3 weeks after the cough starts.

What are the symptoms?

Pertussis starts like a common cold with symptoms such as sneezing, runny nose, mild fever and a mild cough. 
Over the next 2 weeks, the cough worsens, leading to severe, repeated, and forceful coughing spells that often end with a whooping sound before the next breath. The cough can last several months and occurs more often at night. It can make a person gag or spit out mucous, making it hard to breathe. In babies, pertussis can cause periods of apnea in which their breathing is interrupted. 
Babies under 6 months old, teenagers, and adults may not make the whooping sound. Therefore, anyone who could have been exposed to pertussis and who has a cough that lasts more than 1 week should see a health care provider.

What are the risks of the disease?

Pertussis can cause complications such as pneumonia, seizures, brain damage or even death. These complications happen most often in infants under 1 year of age. 
Each year in Canada, 1 to 3 deaths occur due to pertussis, mostly in babies less than 3 months of age who have not been immunized.
Hepatitis B

What is Hepatitis B?

Hepatitis B is a virus that attacks the liver. Most people who get it have it for a short time and then get better. This is called acute hepatitis B. Sometimes, the virus causes a long-term infection called chronic hepatitis B. Over time, it can damage your liver. Babies and young children infected with the virus are more likely to get chronic hepatitis B.

How does it spread?

The hepatitis B virus is spread from one infected person to another by contact with blood or body fluids. This includes an accidental or intentional poke with a used needle, being splashed in the mouth, nose, or eyes with infected blood, being bitten by an infected person, sharing items that may have blood on them such as a toothbrush, dental floss or razor, and by having unprotected sex with someone infected with the hepatitis B virus. People who are infected with hepatitis B virus can pass the virus to their newborn babies during delivery.

What are the symptoms?

After the virus enters your body, it usually takes 2 to 3 months to develop symptoms or signs of illness. Symptoms of hepatitis B may include fatigue, fever, nausea and vomiting, loss of appetite, abdominal pain, dark urine, pale stools and jaundice (yellowing of the skin and eyes). Many people who get hepatitis B show no symptoms and may not know they have the disease. Whether there are signs of illness or not, you can pass the virus on to others.

What are the risks of the disease?

Hepatitis B can cause serious disease, including permanent liver damage (cirrhosis). Hepatitis B is also one of the main causes of liver cancer, which can be fatal.
Most adults will recover, but infants and younger children are more likely to develop long-lasting (chronic) hepatitis B infection. If an infant or young child gets hepatitis B, there is a 90% chance that they will have the disease for life.

What is Polio?

Polio is a disease caused by infection with a virus. Due to immunization, polio has been eliminated in most parts of the world. In 1994, Canada was certified as a “polio free” country. However, until polio is eliminated globally, immunization is the best protection.

How does it spread?

Polio can be spread by contact with the bowel movements (stool) of an infected person. This can happen from eating food or drinking water contaminated with stool.

What are the symptoms and risks?

While most polio infections show no symptoms, others can result in paralysis of arms or legs and even death. Paralysis occurs in about 1 in 200 people infected with the polio virus. 
Haemophilus influenzae type b (Hib)

What is Haemophilus influenzae type b (Hib)?

Hib infection is caused by the Haemophilus influenza type b bacteria. It usually infects children under 5 years of age. Hib can cause serious and life-threatening illnesses, such as bacterial meningitis (inflammation of the lining of the brain) and septicemia (infection of the blood).

How does it spread?

Hib spreads from person to person through coughing, sneezing or close face-to-face contact. Some people don’t have symptoms but can still spread the disease. Babies and children can become sick through sharing soothers, bottles or toys used by other children.

What are the symptoms and risks?

Hib infection usually starts suddenly with:
  • Fever
  • Vomiting
  • Lack of energy
  • Confusion
  • Headache
  • Stiff neck
Hib can cause serious and life-threatening infections, including meningitis (an infection of the lining that covers the brain) and septicemia (an infection of the blood).
For every 20 children who get sick, 1 may die. Permanent complications of infection include brain damage and deafness.
Hib bacteria can also cause a serious and life-threatening infection in the throat called epiglottitis. A child with this infection may have severe difficulty breathing and may need an emergency operation to help breathe.