Are 5 boosters of the DTaP really necessary for all disease...

Question: 

Are 5 boosters of the DTaP really necessary for all disease components? (Measles only require 2)

Answer: 

Getting each recommended vaccine dose according to the BC routine immunization schedule is necessary to provide the best protection possible. Most vaccines require more than one dose to build high enough immunity to prevent disease, boost immunity that fades over time and make sure people who did not get immunity from a first dose are protected. 

The immune or antibody response to inactivated vaccines (e.g., DTaP containing vaccines) is different from the response to live attenuated vaccines (e.g., measles, mumps, rubella (MMR) and varicella vaccines).  

Inactivated vaccines often require multiple doses to build an adequate and lasting immune response.  In general, the first dose primes the immune system and a protective immune response develops after the second or third dose.  These initial doses are called primary vaccination or the primary series. Because protection following primary vaccination may diminish over time, periodic supplemental doses may be required to increase, or “boost,” protection.

Live attenuated vaccines typically produce immunity in most recipients with one dose (except those administered orally). However, a second dose helps to make sure that almost everyone is protected, because some individuals may not respond to the first dose. 

The routine schedule is based on the best science of today and is designed to provide children with the maximum achievable protection, as early as possible.

For more information on how vaccines work and the basis of recommendations for their use, visit: http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/prinvac.pdf.

If you have further questions, we recommend that you speak with your health care provider. 

Date last updated: 
Friday, Sep 19, 2014
Date last reviewed: 
Wednesday, Nov 01, 2017